Radiosurgery

This page contains recent news articles, when available, and an overview of Radiosurgery but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

News: Radiosurgery

Radiosurgery Proves Viable for Some Pancreatic Cancers   -  Sep 21, 2008
By Kevin McKeever. MONDAY, Sept. 22 (HealthDay News) -- A preliminary study shows that radiosurgery may be a viable treatment for recurring pancreatic ... ABC News

First patients treated in India using CyberKnife radiosurgery   -  Apr 6, 2009
Sunnyvalle, Calif. (ANTARA News/PRNewswire-AsiaNet) -- Accuray Incorporated (Nasdaq: ARAY), a global leader in the field of radiosurgery, announced today ... ANTARA

Benefits of CyberKnife Radiosurgery for Lung Cancer Drive Continued …   -  Feb 5, 2010
SUNNYVALE, Calif., Feb 05, 2010 /PRNewswire via COMTEX/ ---- Accuray Incorporated (Nasdaq: ARAY), a global leader in the field of radiosurgery, ... FOXBusiness

Accuray Introduces the CyberKnife(R) VSI(TM) System   -  Nov 1, 2009
Robotic Radiosurgery System has established itself as a leader in full body ... The CyberKnife VSI System leverages the benefits of radiosurgery -- such as ... Wall Street Journal

Pituitary adenomas: is Gamma Knife ® radiosurgery safe?   -  May 19, 2005
Gamma Knife ® (Elekta Corporation, Stockholm, Sweden) radiosurgery has been used to treat more than 20000 patients with pituitary adenoma. ... Nature.com

Radiosurgery and Whole-Brain Radiation Therapy for Brain Metastases   -  Jun 7, 2006
Brain metastases are the most feared and debilitating complication of systemic cancers. They affect approximately 170 000 patients a year, with the most ... Journal of American Medical Association - Journal of American Medical Association...

Radiosurgery for brain cancer OK for elderly   -  Sep 30, 2008
NEW YORK (Reuters Health) - People 75 years of age and older with cancer that has spread to the brain respond about as well as younger patients to ... Reuters UK

Cyberknife radiosurgery minimises damage to healthy tissues   -  Mar 8, 2009
Kolkata (PTI): Cyberknife stereotactic radiosurgery, a new mode of radio surgery, has proved to be more effective in killing tumours and help minimise ... The Hindu

PRICE UPBEAT AFTER PROCEDURE ; RADIOSURGERY PERFORMED …   -  Feb 11, 2005
A.J. Price, his mother, Inga, and father, [Tony Price], were all smiles Thursday in the UConn men's basketball office, only hours after the freshman ... Pay-Per-View - Hartford Courant - ProQuest Archiver

The evolving role of radiosurgery for metastatic spine tumors   -  May 21, 2007
Gerszten PC et al. (2007) Radiosurgery for spinal metastases: clinical experience in 500 cases from a single institution. Spine 32: 193–199 PubMed ... Nature.com

Is stereotactic radiosurgery the best treatment option for patients...   -  Feb 14, 2007
Gerszten PC et al. (2007) Radiosurgery for spinal metastases: clinical experience in 500 cases from a single institution. Spine 32: 193–199 PubMed ... Nature.com

Does radiosurgery have a role in the treatment of acromegaly?   -  Jun 23, 2008
Radiosurgery can be considered as a possible alternative to lifelong medical treatment for those patients with acromegaly in whom transsphenoidal surgery ... Nature.com

Stereotactic Radiosurgery   -  Jan 22, 2009
Stereotactic radiosurgery is a form of radiation therapy that focuses high-powered x-rays on a small area of the body. With regular radiation therapy ... New York Times

Pharmacyclics drug helps find brain cancer-study   -  Jun 3, 2007
He said patients eligible for radiosurgery usually have just a few lesions. "We give them radiosurgery in order to try to control the disease for a longer ... Reuters UK

… the CyberKnife(R) System, the first robotic radiosurgery system in...   -  Sep 2, 2009
MONTREAL (CNW) - In operation since recently at the Centre hospitalier de l'Universit De de Montr Deal (CHUM), the CyberKnife(R) Robotic Radiosurgery System ... CanadianBusiness.com

Warren v. Erickson, No. CV-03-5593 (D.Minn. 03/07/2006)   -  Mar 7, 2006
To treat the ruptured AVM, Warren underwent stereotactic radiosurgery on May 26, 2000. Radiosurgery is the application of a narrow beam of radiation in a ... $2.95 - U.S. District Court, District of... - VersusLaw

Device takes sharp aim at cancer: NorthEast's robotic CyberKnife...   -  Jul 1, 2007
Ads call it "the world's most accurate robotic radiosurgery device. ... It's called radiosurgery because, in some cases, it replaces surgery with bloodless, ... Free with registration - Charlotte Observer - AccessMyLibrary.com

Noninvasive radiosurgery system sets up shop at Roper .   -  Jan 28, 2008
BY JILL COLEY The Post and Courier . Perry Mappus, wore a black leotard with white stripes as Roper Hospital staff helped her slide into a body-hugging ... Post And Courier - Google News Archive

American Shared Hospital Services Announces Contract to Supply a …   -  Feb 4, 2010
AMS is the world leader in providing Gamma Knife radiosurgery equipment, a non-invasive treatment for malignant and benign brain tumors, ... FOXBusiness

Surgery May Help Giant Achieve NBA Dreams   -  Nov 28, 2006
The procedure, called Gamma Knife stereotactic radiosurgery, uses beams of ... "Gamma Knife radiosurgery works by very precisely delivering gamma rays to a ... ABC News

Accuray Incorporated to Present at 28th Annual JP Morgan Healthcare …   -  Dec 16, 2009
The CyberKnife Robotic Radiosurgery System is the world's only robotic radiosurgery system designed to treat tumors anywhere in the body non-invasively. ... Wall Street Journal

Advanced machine for radiotherapy   -  Jan 3, 2010
Currently, around 80 patients with brain tumours or abnormalities are treated each year with stereotactic radiosurgery and it is hoped with the new machine ... BBC News

Proton Radiotherapy for Tumors   -  Oct 9, 2006
In Gamma Knife radiosurgery, the gamma radiation beams are focused on specific tumor to generate enough energy to destroy tissue. The gamma rays work on the ... 央视国际

Accuray Hires General Manager for Japan   -  Nov 13, 2009
The CyberKnife Robotic Radiosurgery System is the world's only robotic radiosurgery system designed to treat tumors anywhere in the body non-invasively. ... Wall Street Journal

… can fractionated radiotherapy and stereotactic radiosurgery be...   -  Aug 6, 2007
Kong DS et al. (2007) The efficacy of fractionated radiotherapy and stereotactic radiosurgery for pituitary adenomas: long-term results of 125 consecutive ... Nature.com

Gamma Knife Radiosurgery .   -  Mar 31, 2005
Pain and electrical sensations in the face can be symptoms of neuralgia, a neurological condition. Those who suffer with this intense pain now have a ... St. Petersburg Times - Google News Archive

Benefits Of Stereotactic Radiosurgery .   -  Dec 2, 2008
...five treatments delivered over course of week compared to the usual three to nine weeks of radiation treatment. To learn more about the Insti tute of ... Reading Eagle - Google News Archive

Accuray Introduces First And Only Radiosurgery Products Designed For ...   -  Nov 7, 2006
Accuray Incorporated, the global leader in the field of robotic radiosurgery, today introduced three new products designed to improve the way lung cancer is ... Medical News Today - Medical News Today (press release)

Joint research in radiosurgery likely   -  Mar 13, 2009
Pratap C. Reddy (left), Chairman of Apollo Hospitals Group, and John R. Adler, Jr. Professor of Radiation Oncology and Neurosurgery, Stanford University, ... Hindu

… radiotherapy versus stereotactic radiosurgery for pituitary...   -  Nov 5, 2007
Kong DS et al. (2007) The efficacy of fractionated radiotherapy and stereotactic radiosurgery for pituitary adenomas: long-term results of 125 consecutive ... Nature.com

Plucky lass needs funds for radiosurgery   -  Dec 27, 2008
YVONNE Foong, the plucky 22-year-old who won the 2005 Dream Malaysia Most Outstanding Youth of the Year award and author of I'm Not Sick, Just A Bit Unwell, ... Malaysia Star

Treating multiple brain tumors with radiosurgery results in improved ...   -  Oct 20, 2005
Treating four or more brain tumors in a single radiosurgery session resulted in improved survival compared to whole brain radiation therapy alone, ... Medical News Today - Medical News Today (press release)

… (R) System As The Only Extracranial Radiosurgery Device In Widesprea...   -  Mar 20, 2007
Accuray Incorporated (Nasdaq: ARAY), a global leader in the field of radiosurgery, announced today the results of an independent survey that confirms that ... Medical News Today - Medical News Today (press release)

Deutsche Bank raises Alliance Imaging to buy   -  May 16, 2008
The company opened two fixed-site imaging centers and acquired six stereotactic radiosurgery facilities during the first quarter. ... Reuters India

Long-Term Survival Possible After Radiosurgery for Brain Metastases   -  Jan 12, 2006
By Will Boggs, MD. NEW YORK JAN 12, 2006 (Reuters Health) - Many patients can survive for years after effective gamma knife radiosurgery for brain ... Cancerpage.com

Benefits Of CyberKnife Radiosurgery For Lung Cancer Drive Continued …   -  Feb 6, 2010
Accuray Incorporated (Nasdaq: ARAY), a global leader in the field of radiosurgery, announced that more than 12000 courses of lung cancer treatment have been ... Medical News Today - Medical News Today (press release)

Price to have radiosurgery   -  Feb 6, 2005
..."It's definitely a relief that they know what it is, that they can start treating it," said [Price], who had an angiogram on Jan. ... Pay-Per-View - Newsday - ProQuest Archiver

Former New Baden resident undergoes radiosurgery to halt malignant …   -  Apr 19, 2006
Former New Baden resident Cody Strout, underwent gamma knife radiosurgery last Wednesday .to halt the growth of brain tumor that has been deemed inoperable ... The Sun - Google News Archive

Doctors, patients say 'Grey's' cancer story isn't accurate   -  May 17, 2009
Wendy Zocks, a Los Angeles publicist, credits radiosurgery with saving her life. ... Only after the radiosurgery, when her doctors confirmed her brain tumor ... USA TODAY - USA Today

… Cancer Patients Treated With The CyberKnife® Robotic Radiosurgery ...   -  Apr 18, 2007
Accuray Incorporated (Nasdaq: ARAY), a global leader in the field of radiosurgery, today announced that its CyberKnife® Robotic Radiosurgery System has been ... Medical News Today - Medical News Today (press release)

Accuray delays Q1 earnings report Silicon Valley / San Jose Business ...   -  Oct 29, 2008
Sunnyvale-based Accuray (NASDAQ:ARAY), which focuses on radiosurgery, said it will hold its first quarter earnings release call on Nov. 6. ... Bizjournals.com

Radiosurgery company income rises 44% San Francisco Business Times   -  Jan 31, 2005
San Francisco-based American Shared Hospital Services said its income for 2004 rose 44 percent compared with last year. The company (AMEX:AMS) said in a ... San Francisco Business Times

… LifeSciences Partners With Siemens to Deliver Stereotactic Radiosur...   -  Nov 4, 2006
More than 350 XKnife(TM) radiosurgery systems have been installed worldwide. Unlike conventional surgery, XKnife(TM) radiosurgery is completely non-invasive ... primezone.com

… radiotherapy and stereotactic radiosurgery for pituitary adenomas   -  Sep 13, 2007
Single-dose radiosurgery produces a more prompt effect than FRT on the hypersecretion of pituitary hormones and can be recommended over FRT in some ... Nature.com

The Fastest and Most Accurate Radiosurgery System Now Eliminates …   -  May 6, 2005
SUNNYVALE, Calif., May 6 /PRNewswire/ -- Marking a major advance in non-invasive surgery, Accuray(TM) has introduced the Xsight(TM) Spine Tracking System, ... $4.95 - PR Newswire - ECNext

Elekta wins Australian hospital cancer treatment order   -  May 2, 2008
Included in the order is the Leksell Gamma Knife Perfexion for non-invasive radiosurgery, Elekta Synergy digital linear accelerator systems for intensity ... Forbes

… Journal Issues Supplement Dedicated to CyberKnife Radiosurgery …   -  Jan 30, 2009
The benefits of the CyberKnife System's ability to perform radiosurgery ... The CyberKnife Robotic Radiosurgery System is the world's only robotic ... Genetic Engineering News - Genetic Engineering News (press release)

Accuray Introduces Radiosurgery Products Designed for the Non...   -  Oct 6, 2006
Accuray, a company focused on the field of robotic radiosurgery, is rolling out three new products designed to improve the way lung cancer is treated. ... Free with registration - Wireless News - AccessMyLibrary.com

The Fastest and Most Accurate Radiosurgery System Now Eliminates …   -  May 9, 2005
Marking a major advance in non-invasive surgery, Accuray(TM) has introduced the Xsight(TM) Spine Tracking System, which integrates with the CyberKnife(R) ... Medical News Today - Medical News Today (press release)

Elekta's Gamma Knife Perfexion gets regulatory approval in Japan   -  May 26, 2008
...at new and existing customer sites in Japan. Gamma Knife surgery is the world's most widely used radiosurgery treatment for brain tumours, Elekta said. Forbes

Stereotactic Radiosurgery A Viable Treatment Option For Select...   -  Apr 22, 2007
An estimated 1.4 million new cases of all types of cancer will be diagnosed in 2007, and more than 559000 estimated deaths will occur. ... Medical News Today - Medical News Today (press release)

Accuray Ranked 155th Fastest Growing Company in North America on …   -  Oct 20, 2009
The CyberKnife Robotic Radiosurgery System is the world's only robotic radiosurgery system designed to treat tumors anywhere in the body non-invasively. ... Bizjournals.com

Accuray reports growing acceptance of CyberKnife robotic radiosurgery...   -  May 9, 2006
..."We have known for some time that radiosurgery is an effective treatment for ... We can now offer an effective radiosurgery treatment option for our ... MTBeurope

The Fastest and Most Accurate Radiosurgery System Now Eliminates …   -  May 10, 2005
Marking a major advance in non-invasive surgery, Accuray(TM) has introduced the Xsight(TM) Spine Tracking System, which integrates with the CyberKnife(R) ... i-newswire.com

CyberKnife Radiosurgery Used To Treat Lung Tumors At 90% Of Centers …   -  Mar 27, 2008
Accuray Incorporated (Nasdaq: ARAY), a global leader in the field of radiosurgery, announced that approximately 90 percent of CyberKnife centers worldwide ... Medical News Today - Medical News Today (press release)

Cancer treatment made easy with hi-tech facilities in India   -  Feb 4, 2010
It is a painless, non-invasive approach to radiosurgery that results in fewer ... “It is one of the most precise, non-invasive radiosurgery treatments ... Thelatest News

ROBOTIC RADIOSURGERY; Gamma Knife vs. Cyberknife   -  Nov 9, 2007
Stereotactic radiosurgery (SRS) is a non-surgical (no incision) treatment that delivers an ultra-precise high doses of focused radiation from multiple ... News Today Online

Accuray shares fall on weak revenue outlook   -  Aug 25, 2009
...expectations by a penny, and said it added $75 million to backlog representing 15 CyberKnife robotic radiosurgery system agreements during the period. ... Forbes

Treating Multiple Brain Tumors with Radiosurgery Results in Improved ...   -  Oct 25, 2005
Treating four or more brain tumors in a single radiosurgery session resulted in improved survival compared to whole brain radiation therapy alone, ... emaxhealth.com

Non-Invasive Radiosurgery With Novalis Tx(TM) Platform Rolling Out …   -  Sep 22, 2008
PALO ALTO, Calif., and WESTCHESTER, Ill., Sept. 22 /PRNewswire-FirstCall/ -- Doctors around the globe are turning more and more to the use of stereotactic ... RedOrbit

Brain Cancer .   -  Jun 12, 2006
Stereotactic radiosurgery is a more focused, non-invasive radia tion treatment ... Should patients receive stereotactic radiosurgery or com bine it with ... Milwaukee Journal Sentinel - Google News Archive

Varian Medical Systems receives FDA clearance for new radiosurgery …   -  Sep 18, 2007
The new HD120 MLC multileaf collimator enables clinicians to deliver extremely precise radiosurgical treatments, including intensity-modulated radiosurgery ... News-Medical.net

Focused Radiation May Help Some With Lung Cancer   -  Nov 3, 2009
Collins has been a paid clinical consultant for Accuray. The Radiological Society of North America has more about stereotactic radiosurgery. ABC News

Treating multiple brain tumors with radiosurgery results in improved ...   -  Oct 17, 2005
DENVER, Oct. 18 ñ Treating four or more brain tumors in a single radiosurgery session resulted in improved survival compared to whole brain radiation ... PsychCentral.com

ORLive Presents: Gamma Knife Radiosurgery Treatment for an Acoustic …   -  Dec 18, 2006
Gamma Knife radiosurgery for an acoustic neuroma will be featured on the sixth webcast sponsored by Saint Joseph's Hospital and Marshfield Clinic. ... Genetic Engineering News - Genetic Engineering News (press release)

… (R) System as the Only Extracranial Radiosurgery Device in Widesprea...   -  Mar 19, 2007
The survey concludes that hospitals with combined radiotherapy and radiosurgery systems, also known as "all-purpose" units, are rarely utilizing the ... Free with registration - PR Newswire - AccessMyLibrary.com

… to Link CyberKnife(R) Robotic Radiosurgery System With MOSAIQ(R) E   -  Sep 16, 2008
Accuray develops and markets the CyberKnife Robotic Radiosurgery System, which extends the benefits of radiosurgery to include extracranial tumors, ... RedOrbit

… Results Published On Patients Treated With CyberKnife Radiosurgery   -  Oct 2, 2009
CyberKnife prostate radiosurgery is a non-invasive, outpatient treatment that is ... The CyberKnife Robotic Radiosurgery System is the world's only robotic ... Medical News Today - Medical News Today (press release)

… : Comprehensive Resource on Robotic Radiosurgery Published by the …   -  Oct 13, 2005
Comprehensive Resource on Robotic Radiosurgery Published by the CyberKnife(R) Society Press. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Gamma Knife treatment for stereotactic radiosurgery in the brain and ...   -  Nov 8, 2006
The Bupa Cromwell Hospital, London, are delighted to announce that they will be the first Hospital in the UK to commission the Leksell Gamma Knife® ... Private Healthcare UK

… Acquisition of Six Radiosurgery CyberKnife Stereotactic Facilities...   -  Apr 7, 2008
Alliance Radiosurgery, LLC, has purchased the assets of six stereotactic ... CyberKnife® Robotic Radiosurgery System located in California, Maryland, ... RedOrbit

… : ORLive Presents: Gamma Knife Radiosurgery Treatment for an...   -  Jan 17, 2007
Gamma Knife radiosurgery for an acoustic neuroma will be featured on the sixth webcast sponsored by Saint Joseph's Hospital and Marshfield Clinic. ... Genetic Engineering News - Genetic Engineering News (press release)

… Code - 3701-84-67 Radiation therapy and stereotactic radiosurgery ...   -  Aug 16, 2005
...(2) Each stereotactic radiosurgery service shall establish policies and procedures to ... If the stereotactic radiosurgery service is unable to conduct the ... Pay-Per-View - Ohio Administrative Code - Loislaw

… FDA Clearance for stereotactic radiosurgery Leksell Gamma Knife …   -  Aug 30, 2006
Elekta has received US FDA 510(k) pre-market clearance to market its Leksell Gamma Knife Perfexion stereotactic radiosurgery system in the US ... MTBeurope

CyberKnife to be Focus of Numerous Presentations at the American …   -  Oct 30, 2009
Robotic Radiosurgery System to treat tumors located throughout the body ... To date, CyberKnife radiosurgery has been used to treat more than 4000 men with ... Wall Street Journal

Accuray IPO Raises $288M   -  Feb 8, 2007
Its lead product, CyberKnife, first garnered US approval in 1999 to provide treatment planning and image-guided radiosurgery for tumors in the head and neck ... Red Herring

… CyberKnife(R) System Most Widely Used Extracranial Radiosurgery …   -  Mar 7, 2008
In its second year, this survey charts the rapid growth of radiosurgery ... "As a result, the market for extracranial radiosurgery is growing universally. ... Medical News Today - Medical News Today (press release)

Price must sit out UConn season   -  Jan 7, 2005
The good news is the mass of abnormal blood vessels that has formed on the left side of Price's brain can be eradicated through radiosurgery, a one-time ... Pay-Per-View - Newsday - ProQuest Archiver

… Performed Using Novalis Tx(TM) Radiosurgery Technology in IndiaYoung...   -  Sep 30, 2009
..."Following Novalis Tx radiosurgery treatment the patient's symptoms had alleviated ... The Novalis Tx radiosurgery platform features very high dose delivery ... Benzinga

Dose deviation during stereotactic radiosurgery treatments   -  Jun 18, 2007
On 20 April 2007, the French Nuclear Safety Authority (ASN) was informed of a deviation between the delivered dose and the prescribed dose to 145 patients ... World Nuclear News

Radiosurgery centers expect to open in Bay area   -  Oct 22, 2007
A non-invasive radiosurgery device that can be used to treat cancer is poised to enter the Tampa Bay market. Tampa Bay Radiosurgical Associates LLC said it ... Tampa Bay Business Journal

Second European Radiosurgery Workshop Yields Record Attendance   -  Apr 11, 2009
Attendance Doubles with More Than 200 Health Professionals From 28 Countries Participating Accuray Incorporated (Nasdaq: ARAY), a global leader in the field ... Medicexchange

Press Release: Latest Robotic Radiosurgery Studies Presented at the...   -  Feb 7, 2006
Latest Robotic Radiosurgery Studies Presented at the 5th Annual CyberKnife(R) Society Users' Meeting. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

… Neurosurgery Meeting Highlight Benefits of CyberKnife Radiosurgery...   -  May 5, 2009
The presentations highlight outcomes with CyberKnife radiosurgery including ... "We recognize that the basis of radiosurgery was formed around these ... Pay-Per-View - PR Newswire - HighBeam Research

[U] Radiosurgery New York LLC v. Cabrini Medical Center, 19 Misc.3d …   -  Mar 13, 2008
This matter came before the Court, pursuant to an Order to Show Cause, wherein plaintiff's petition alleged that Cabrini Medical Center breached a contract ... $2.95 - Supreme Court of New York, X County - VersusLaw

Radiosurgery In Early Prostate Cancer   -  Mar 27, 2009
Winthrop-University Hospital's Advances in Cancer Care educational series will offer a free program, "Using CyberKnife(r) Radiosurgery in Early Prostate ... Garden City News

New Radiogun Leads to More Powerful Stereotactic Radiosurgery …   -  Sep 19, 2007
Intensity Modulated Radiotherapy (IMRT), a modality known for its high precision in delivering radiation to a precise location within the contours of a ... Medgadget.com

Accuray Incorporated to Report Financial Results for Second Quarter...   -  Jan 13, 2010
The CyberKnife Robotic Radiosurgery System is the world's only robotic radiosurgery system designed to treat tumors anywhere in the body non-invasively. ... FOXBusiness

CyberKnife Radiosurgery for Lung Cancer Sees Increased Interest and …   -  Mar 2, 2009
SUNNYVALE, Calif. , March 2 /PRNewswire-FirstCall/ -- Accuray Incorporated (Nasdaq: ARAY), a global leader in the field of radiosurgery, announced today ... RedOrbit

CyberKnife Radiosurgery Used to Treat More Than 3,000 Prostate …   -  Apr 23, 2009
PRNewswire-FirstCall/ -- Accuray Incorporated, a global leader in the field of radiosurgery, announced today that more than 3000 prostate cancer patients ... UroToday International Journal

… Dedicated to CyberKnife Radiosurgery Experience. - PR New   -  Jan 30, 2009
The benefits of the CyberKnife System's ability to perform radiosurgery ... Robotic Radiosurgery System. The CyberKnife System at Fox Chase ... techniques. ... Pay-Per-View - PR Newswire - HighBeam Research

Accuray beefs up board with two CFOs   -  Sep 15, 2009
Radiosurgery business Accuray Inc. added former Genentech CFO Louis Lavigne Jr. to its ... The business makes a robotic radiosurgery device to treat tumors. Bizjournals.com

… First Novalis Tx(TM) Radiosurgery Platform Begins Radiotherapy …   -  Oct 14, 2009
RIGA, Latvia, Oct. 14 /PRNewswire-FirstCall/ -- Doctors in Latvia have begun treatments using the region's first Novalis Tx(TM) radiosurgery platform from ... Benzinga

Press Release: Second European Radiosurgery Workshop Yields Record …   -  Apr 10, 2009
Second European Radiosurgery Workshop Yields Record Attendance. from PR Newswire Europe. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire Europe - HighBeam Research

Accuray's Q4 profit drops on 16% higher revenue   -  Aug 19, 2008
Accuray Inc., which focuses on radiosurgery, said Tuesday it had fourth quarter net income of $191000, or breakeven, down from $502000, or a penny a share ... Bizjournals.com

Robotic Radiosurgery Course Yields Record Attendance   -  May 5, 2008
SUNNYVALE, Calif., May 5 /PRNewswire-FirstCall/ -- Accuray Incorporated , a global leader in the field of radiosurgery, today announced that the Robotic ... RedOrbit

Press Release: Robotic Radiosurgery Course Yields Record Attendance. ...   -  May 5, 2008
Robotic Radiosurgery Course Yields Record Attendance. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Press Release: CyberKnife Radiosurgery Used to Treat More Than 3,000 ...   -  Apr 23, 2009
CyberKnife Radiosurgery Used to Treat More Than 3000 Prostate Cancer Patients Worldwide. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Second European Radiosurgery Workshop Yields Record …   -  Apr 10, 2009
Second European Radiosurgery Workshop Yields Record Attendance. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

New resource on robotic radiosurgery   -  Nov 3, 2005
Sunnyvale, Calif, USA. The CyberKnife Society Press has published Robotic Radiosurgery - Volume 1, which it claims is the most extensive and well-documented ... MTBeurope



Background information on Radiosurgery [When available]

Radiosurgery is a medical procedure which allows non-invasive brain surgery, i.e., without actually opening the skull, by means of directed beams of ionizing radiation. It is a relatively recent technique (1951), which is used to destroy, by means of a precise dosage of radiation, intracranial tumors and other lesions that could be otherwise inaccessible or inadequate for open surgery. There are many nervous diseases for which conventional surgical treatment is difficult or has many deleterious consequences for the patient, due to arteries, nerves, and other vital structures being damaged.

Definition and applications

Radiosurgeons make use of highly sophisticated, highly precise and complex instruments, such as stereotactic devices, linear accelerators, computers and laser beams. In the last 20 years, radiosurgery has been used as a first approach, by exclusion or failure of other techniques or as supplements to them, such as other kinds of brain surgery, chemotherapy and radiotherapy. The highly precise irradiation of targets within the brain is planned by the surgeon with basis on images, such as computed tomography (CT), magnetic resonance imaging (MRI), and angiography of the brain. The radiation is applied coming from an external source, under precise mechanical orientation by a specialized apparatus. Multiple beams are directed (collimated) and centered at the intracranial lesion to be treated. In this way, healthy tissues around the target are preserved.

Patients can be treated within one day of hospital stay, or even as outpatients. By comparison, the average hospital stay for a craniotomy (conventional neurosurgery, requiring the opening of the skull) is about 15 days. Radiosurgery costs about the same as a conventional surgery, but it avoids mortality, pain and post-surgical complications, such as hemorrhage and infection. The period of recovery is minimal, and in the day following the treatment the patient may return to his or her normal life style, without any discomfort. Thus, the community gains many socio-economical benefits. The major disadvantage of radiosurgery in relation to open surgery (craniotomy) it is the duration of time required to achieve the desired effects, while its non-invasive character is perhaps its major advantage.

Radiosurgery has arisen as the result of many scientific developments which have occurred in the fields of neuroimaging and stereotactic surgery, continue to expand its application areas in neurosurgery, oncology (cancer), surgery of head and neck, and other specialties.

History

Radiosurgery started with Dr. Lars Leksell from the Karolinska Institute of Stockholm, Sweden, in 1959, in a joint development with Bjorn Larsson, a radiobiologist from Uppsala University. Leksell initially used heavy particles, protons from a to irradiate brain tumor lesions.

In 1968, they developed the "gamma knife", a new device exclusively for radiosurgery, which consisted of radioactive sources of Cobalt-60 placed in a kind of helmet with central channels for irradiation, using gamma rays. In the last version of this device, 201 sources of radioactive cobalt direct gamma radiation to the center of a helmet, where the patient's head is inserted.

In order to achieve high precision in the positioning of the patient's head, it is placed first on a rigid frame of reference called a stereotactic device. It uses a geometrical coordinate system for each structure of the brain, so the surgeon knows, by using a published atlas, precisely the point where the gamma rays must converge. The stereotactic frame then fits into the helmet.

The "Gamma-knife" is used nowadays in four continents for carrying out what is called functional stereotactic neurosurgery, and for the superselective irradiation of tumors and brain arteriovenous malformations.

Another type of radiosurgery which has enjoyed great dissemination in neurosurgery was introduced by Betti and Colombo, in the mid 80's, utilizing commercial medical linear accelerators available for radiation therapy in oncology (the so-called LinAc). High energy, narrowly focused beams of x-rays are employed.

This system differs from the Gamma Knife in the way the radiation beams are delivered to the patient's head. In a similar way, a stereotactic device is used to provide a geometric coordinates reference, but the radiation beams are emitted by a single source, which rotates slowly around the patient's head.

Finally, at some medical centers such as in Boston and in California, particle accelerators built for doing research in high energy physics have been used since the 1960's for the treatment of brain tumors and brain arteriovenous malformations in humans. A still experimental type of radiosurgery, that utilizes a nuclear reactor for the nuclear fission of uranium, is the Neutron Capture Therapy (NCT) which was started in the United States at the nuclear reactor of the Massachusetts Institute of Technology (MIT) in the 60's, with promising results. Nowadays it is carried out as a promising advanced clinical research in several countries, due to the progress and to the results obtained in Japan by Dr. Hiroshi Hatanaka. He used NCT in more than 100 cases in the treatment of malignant tumors and of gigantic arterio-venous malformations.

How it works

The fundamental principle of radiosurgery is that of selective ionization of the tissue to be operated upon, by means of high-energy beams of radiation. Ionization is the production of inorganic ions which are usually deleterious to the cells, by forming free radicals that are harmful to the cellular and nuclear membranes, and even to the RNA and DNA chains of the cells, producing an irreparable damage to these structures and then the cell's death. Thus, biological inactivation is carried out in a volume of tissue to be treated, with a precise destructive effect. The radiation dose absorbed by the treated mass of tissue is what defines the degree of biological inactivation. It usually is measured in Gray units, where one Gray (Gy) is the absorption of one joule per kg of mass.

In order to perform optimal therapy, the neurosurgeon, assisted by physicists specialized in nuclear medicine and often in conjunction with a radiation oncologist, chooses the best type of radiation to be used, and how it will be delivered. Usually, the total dose of radiation required to kill a tumor, for example, is not delivered in a single, massive section, because this would cause undesirable effects on the patient. Instead, it is divided into several sessions of smaller duration and energy dose, in a procedure called dose fractioning. The aim of dose fractioning is to minimize the undesirable damage to healthy tissues, as healthy tissue cells are better than cancerous cells at repairing radiation induced damage between irradiations. In order to plan the radiation incidence and dosage, the physicists calculate a map portraying the lines of equal absorbed dose of radiation upon the patient's head (this is called a isodose map). Information about the tumor's location is obtained from a series of computerized tomograms, which are then feed to special planning computer software.

There are five types of irradiation currently used in radiosurgery: electromagnetical waves (gamma rays and x-rays), subatomic particles (protons and neutrons), and carbon ions.

The first type of radiation is gamma rays, which are beams of high energy photons that interact with the corona of electrons of the atoms that compose the irradiated tissue, ionizing them. Gamma radiation is used in the "Gamma Knife" device, where they are produced by fixed sources of radioactive cobalt.

The second type of radiation, X-rays, are also high energy photons that are identical to gamma rays except for the way they are produced. Radiosurgery can be performed using a linear accelerator, the source being now a commercial medical device of universal use in radiotherapy. The Linac consists of a emitting tube of X radiation, with an energy of 4, 6, or 18 million electron-volts (MeV).

The emission head (called "gantry") is mechanically rotated around the patient, in a full or partial circle. The table where the patient is lying, the 'couch,' can also be moved in small linear or angular steps. The combination of the movements of the gantry and of the couch makes possible the computerized planning of the volume of brain tissue which is going to be irradiated. Devices with an energy of 6 MeV are the most suitable for the treatment of the brain, due to the smaller volume to be irradiated. In addition, the diameter of the energy beam leaving the emission head can be adjusted to the size of the lesion by means of interchangeable collimators (an orifice with different diameters, varying from 5 to 40 mm, in steps of 5 mm). There are also multileaf collimators, which consist of a number of metal leaflets that can be moved dynamically during treatment in order to shape the radiation beam to conform to the mass to be ablated.

The third type of radiation, protons, is used in Proton Beam Therapy (PBT). Protons are produced by cyclotrons, extracting them from proton donor materials and accelerating them in successive travels through a circular, evacuated conduit, using powerful magnets, until they reach a high energy and are released toward the irradiation target, in the patient's body. Because of the Bragg peak effect, proton therapy has some theoretical advantages over other the other forms of radiation, since most of the proton's energy is deposited within a limited distance, and so tissue beyond this range is spared from the effects of radiation. This property of protons allows for conformal dose distributions to be created around even very irregularly shaped targets. In recent years, however, so-called "intensity modulated" techniques have allowed for similar conformities to be attained using linear accelerator radiosurgery.

Neutrons, the fourth type of radiation, are used in Boron neutron capture therapy (BNCT). BCNT depends on the interaction of slow neutrons with boron-10 to produce alpha particles, another type of radiation. Patients are first given an intravenous injection of a boron-10 tagged chemical that preferentially binds tumor cells. The neutrons are created either in a nuclear reactor or by colliding high-energy protons into a Lithium target. The neutrons pass through a moderator, which shapes the neutron energy spectrum suitable for BNCT treatment. Before entering the patient the neutron beam is shaped by a beam collimator. While passing through the tissue of the patient, the neutrons are slowed by collisions and become low energy thermal neutrons. The thermal neutrons undergo reaction with the boron-10 nuclei, forming an unstable boron-11 nucleus which then undergoes spontaneous decay to lithium-7 and an alpha particle. Both the alpha particle and the lithium ion produce closely spaced ionizations in the immediate vicinity of the reaction, with a range of approximately 10 micrometres, or one cell diameter. This technique is advantageous since the radiation damage occurs over a short range and thus normal tissues can be spared. Also, there are two mechanisms for tumor selectivity, since both the boron compound is made to bind to tumor cells and the neutron beam is aimed at the location of the tumor. BNCT has been developed in only in an experimental basis, and it has not entered surgical routine.

The selection of the proper kind of radiation and device depends on many factors including lesion type, size and location in relation to critical structures. Data suggests that similar clinical outcomes are possible with all of these methods. More important than the device used are issues regarding indications for treatment, total dose delivered, fractionation schedule and conformity of the treatment plan.

Latest generation Linacs are capable of achieving extremely narrow beam geometries, such as 0,15 to 0,3 mm. Therefore, they can be used for several kinds of surgeries which hitherto are carried out by open or endoscopic surgery, such as for trigeminal neuralgia, etc.

Radiosurgery of brain tumors

Radiosurgery has been especially helpful for the localized, highly precise treatment of brain tumors. Due to the steep fall of the irradiation fields (isodoses) from the center of the target to be destroyed, the biological inactivation happens only on it; while the brain, and other vascular and neural structures around it, are protected. This is achieved through the high mechanical precision of the radiation source, and the assured reproducibility of the target. The precision in the positioning of the patient, in the calculation of dosages, and in the safety of the patient, are all extremely high.

Radiosurgery is indicated primarily for the therapy of tumors, vascular lesions and functional disorders. Significant clinical judgment must be used with this technique and considerations must include lesion type, pathology if available, size, location and age and general health of the patient. General contraindications to radiosurgery include excessively large size of the target lesion or lesions too numerous for practical treatment.

The non-interference with the quality of life of the patient in the post-operatory period competes with the inconvenience of the latency of months until the result of the radiosurgery is accomplished. Patients with a bad general state of health and those with tumors which are unreachable by conventional means, are specially helped.

Rbecome may not be evident for months after the treatment. Since radiosurgery does not remove the tumor, but results in a biological inactivation of the tumor, lack of growth of the lesion is normally considered to be treatment success. Radiosurgery has been used to treat many kinds of brain tumors, such as acoustic neuromas, astrocytomas, gliomas, germinomas, meningiomas, among others. Even highly fatal cancerous metastases in the brainstem can be reduced, leaving the patient neurologically intact. It has been demonstrated by the thousands of successfully treated cases, that radiosurgery can be a very safe and efficient method for the management of many difficult brain lesions, while it avoids the loss in quality of life associated to other more invasive methods. For many indications, such as acoustic neuroma, brain arteriovenous malformations and skull base tumors, radiosurgery has emerged as the treatment of choice.

Patients are being treated for lesions which only radiosurgery can solve, or because they prefer it as a first treatment, after receiving complete information of its risks and benefits as compared to the conventional surgery, when the choice is available.

In the future, advanced computer methods, such as intensity-modulated radiosurgery will be used to improve the accuracy and scope of radiosurgery.

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