Pituitary Cancer

This page contains recent news articles, when available, and an overview of Pituitary Cancer but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

News: Pituitary Cancer

Case joins 22 cancer plaintiffs  -  Feb 25, 2008
Northwest Herald,The lawsuit is the second to deal with a liver ailment – 18 of the plaintiffs have brain or nerve cancer, three have pituitary cancer, and one has cirrhosis

Fight of their lives  -  Dec 16, 2007
Northwest Herald,Eighteen of the plaintiffs have brain cancer, three have pituitary cancer, and one has cirrhosis of the liver. Freiwald accuses the companies in the

no increased risk of cancer from oral contraceptives  -  Nov 2, 2007
Irish Medical News,...a 5.5 fold increased risk for cns/pituitary cancer, but a 62 per cent reduction in risk for ovarian cancer. the authors concluded that, for the study

Oral Contraceptive Use Linked to Cancer Risk  -  Sep 17, 2007
Medscape (subscription)...there were statistically significant trends of increasing risk for cervical and central nervous system or pituitary cancer but decreasing risk for

Developing A Modular, Nanoparticle Drug Delivery System  -  Oct 5, 2007
Science Daily (press release)Scientists think that many diseases, including diabetes and certain forms of pituitary cancer, are caused by malfunctioning G proteins.

Background information on Pituitary Cancer [When available]

Pituitary adenomas are tumors that occur in the pituitary gland, and account for about 10% of intracranial neoplasms. They often remain undiagnosed, and small pituitary tumors are found in 6 to 24 percent of adults at autopsy.

Pituitary tumors were, historically, classed as basophilic, acidophilic, or chromophobic on the basis of whether or not they took up the stains hematoxylin and eosin. This classification has fallen into disuse, in favor of a classification based on what type of hormone is secreted by the tumor (though tumors which do not secrete any active hormone ("non-functioning tumors") are still sometimes called "chromophobic").

At present, classification of pituitary tumors is based on plasma hormone levels or immunohistochemical staining:
  • corticotrophic adenomas secrete adrenocorticotropic hormone (ACTH) and pro-opiomelanocortin (POMC)
  • somatotrophic adenomas secrete growth hormone (GH)
  • thyrotrophic adenomas secrete thyroid-stimulating hormone (TSH)
  • This is a rare tumor type, making up <1% of all pituitary adenomas. TSH secretion from these tumors can cause hyperthroidism.[1]
  • gonadotrophic adenomas secrete luteinizing hormone (LH), follicle-stimulating hormone (FSH) and their subunits
  • lactrotrophic adenomas or prolactinomas secrete prolactin
  • null cell adenomas do not secrete hormones, but may stain positive for synaptophysin

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