Interleukin-2

This page contains recent news articles, when available, and an overview of Interleukin-2 but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

News: Interleukin-2

EpiCept Corporation Reports Third Quarter Results, Provides Business Update  -  ‎Nov 9, 2009‎
WELT ONLINECeplene ® (histamine dihydrochloride) administered with low-dose interleukin-2 (IL-2) is the Company's treatment for the remission maintenance and ...

REG-Biocompatibles Intl.: Statement re Positive Data in Combination Therapy Trial  -  ‎Nov 3, 2009‎
ReutersTreatment of patients with advanced renal cell carcinoma who have failed prior interferon-alpha or interleukin-2 based therapy or are considered unsuitable ...

Major Advances in Clinical Cancer Research in 2009: A Report From ASCO  -  ‎Nov 17, 2009‎
MedscapeA phase 3 trial showed that adding the vaccine to standard therapy with interleukin-2 more than doubled the response rate, and increased both ...

FDA Sanctions Gloucester Pharmaceuticals' Cutaneous T-Cell Lymphoma Therapy  -  ‎Nov 6, 2009‎
Genetic Engineering News (press release)For example, Ontak is sanctioned specifically for use in CTCL that expresses the CD25 component of the interleukin-2 (IL-2) receptor. ...

Report Highlights Cancer Advances  -  ‎Nov 9, 2009‎
MedPage TodayA vaccine that boosts the immune system's response to cancer doubled the response rate of melanoma when added to interleukin-2 (IL-2). ...

Incidence of Kidney Cancer Increasing  -  ‎Oct 29, 2009‎
Space Coast Medicine and Healthy LivingDrugs in this category include interferon and interleukin-2, which are synthetic versions of chemicals made in the body. Biological therapy drugs are ...

Melanoma Research Foundation Leads Unprecedented Collaboration for Melanoma ...  -  ‎Nov 3, 2009‎
ReutersInterleukin-2 (IL-2) was the last drug approved to treat advanced melanoma, but 85% of patients derive no benefit from this drug. The Consortium approach to ...

Phase I trial of an allogeneic gene-modified tumor cell vaccine (RCC-26/CD80 ...  -  ‎Oct 29, 2009‎
UroToday...line RCC-26 displayed natural immunogenic potential that was enhanced through expression of CD80 costimulatory molecules and secretion of interleukin-2. ...

BioVex's $70M Series F to Fund Pivotal OncoVex Melanoma Trial  -  ‎Nov 10, 2009‎
Therapeutics Daily (press release) (registration)Some metastatic melanoma patients currently are treated with the immunotherapy interleukin-2, and patients who respond usually go into durable remission. ...

Young mom gets help to head south for cancer fight  -  ‎Nov 5, 2009‎
Winnipeg Free PressFor the record, Kaleena's "health insurance" -- government-funded health insurance of course -- covers not only the administering of interleukin 2, ...

More Tysabri Problems; Time for a Biogen-Idec Credibility Check  -  ‎Oct 30, 2009‎
BNET...(TNF)-alpha antagonist Enbrel (Etanercept), the anti-CD52 antibody Campath (alemtuzumab), or the interleukin-2 receptor antibody Simulect (basiliximab). ...

Llega a la Argentina una nueva alternativa terapéutica para el cáncer de riñón.  -  ‎Nov 9, 2009‎
Noticias Médicas (Comunicado de prensa)Además, se admitió a pacientes tratados previamente con bevacizumab, interferón alfa y interleukin-2. Los pacientes evaluados fueron distribuidos, ...

Wie Vitamin B12 bei atopischer Dermatitis wirken soll  -  ‎Oct 28, 2009‎
DAZ.online - Das Internetportal der Deutschen Apotheker ZeitungSie sind verantwortlich für eine erhöhte Produktion von entzündungsfördernden Zytokinen wie Interleukin-1alpha, Interleukin-2, Interleukin-6 und Interferon ...

FDA Calendar Updates: Orexo, Novo Nordisk, King, Isis, Facet  -  07 Aug 2009
Seeking AlphaDaclizumab is a humanized monoclonal antibody that binds to the alpha chain (CD25) of the interleukin-2 (IL-2) receptor on activated T cells,

S/he said  -  07 Aug 2009
pride source.comGreg Louganis, in an article titled "Furry, Cuddly, Lifesaving," recalling the grueling interleukin-2 treatments he was taking to boost his CD4-cell count,

Novel Therapeutics for Melanoma  -  ‎Jul 28, 2009‎
MedscapeHigh-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993. J. Clin. Oncol.

Afinitor® approved in EU as first treatment proven to benefit ...  -  ‎Aug 5, 2009‎
PR-Inside.com (Pressemitteilung)Prior therapy with bevacizumab, interferon alfa and interleukin-2 was allowed. Patients were randomized to receive Afinitor (10 mg) daily or placebo,

Vical and Teva Establish Sales and Marketing Agreement for ...  -  ‎Aug 3, 2009‎
GlobeNewsWire (press release)The toxicity associated with FDA-approved treatments such as dacarbazine or interleukin-2 is often significant, resulting in serious or life-threatening

Long-acting beta-2-agonists have no major anti-inflammatory effects  -  ‎Aug 1, 2009‎
news Stories...neutrophil count, it had no effect on serum interleukin-2 receptor levels or on any inflammatory marker in any of the airway compartments studied.

Prediction of response to combined immunotherapy with interferon ...  -  ‎Jul 21, 2009‎
UroToday...immunotherapy with interferon-alpha (IFN-alpha) and low-dose interleukin-2 (IL-2) and to identify factors predicting susceptibility to this therapy.

Phase I/II open-label study of the biologic effects of the ...  -  ‎Jul 29, 2009‎
7thSpace Interactive (press release)To explore the biological activity of EMD 273063 (hu14.18-IL2), a humanized anti-GD2 monoclonal antibody fused to interleukin-2 (IL2), in patients with

Professor Receives Cancer Institute Award  -  ‎Jul 13, 2009‎
USC NewsThe reagent he developed along with co-worker Peisheng Hu is an analog of Interleukin-2 (IL-2), an important therapeutic for cancer patients.

Flu Shots Not as Effective in Lupus  -  ‎Jul 31, 2009‎
MedPage Today...tumor necrosis factor and interleukin-2 -- was less than half that of controls, both at baseline and after vaccination (P<0.001 for both comparisons).

Bristol's Cancer Bet  -  ‎Jul 23, 2009‎
ForbesAnother immune-boosting therapy against cancer, the natural immune system protein interleukin-2, has been limited by severe side effects.

USC Researcher Wins $3.5M NCI RAID Award to Fund Spinout Pivotal ...  -  ‎Jul 14, 2009‎
GenomeWeb Daily NewsThe most recent RAID award will support preclinical development of an interleukin-2 cytokine immunotherapy analog discovered by Epstein, a professor of

Nexavar® In Combination With Chemotherapy Shown To Extend ...  -  ‎Jul 25, 2009‎
Medical News Today (press release)...advanced renal cell carcinoma (RCC) who have failed prior interferon-alpha or interleukin-2 based therapy or are considered unsuitable for such therapy.

EpiCept begins post-approval clinical study with Ceplene  -  ‎Jul 15, 2009‎
pharmabiz.comCeplene is to be administered in conjunction with low-dose interleukin-2 (IL-2). This study will enrol up to 150 patients at approximately 25 centers across

Clinic fundraisers to aid Hunt family  -  ‎Jul 15, 2009‎
Windsor Star...the only place where he was able to get Interleukin-2, a protein that stimulates the immune system and the production of infection-fighting cells.

Afinitor - nytt hopp för patienter med spridd njurcancer  -  ‎Aug 5, 2009‎
Newsdesk (pressmeddelande)Även patienter som hade behandlats med bevacizumab, interferon alfa och interleukin-2 deltog i studien. Resultaten var så goda att studien avbröts i förtid

Brustkrebs - Überlebenszeit verlängert durch Kombinationstherapie ...  -  ‎Jul 27, 2009‎
Medizin-Aspekte...bei denen eine Behandlung mit Interferon-alpha oder Interleukin-2 nicht angeschlagen hat oder die für eine solche Therapie nicht in Frage kommen.



Background information on Interleukin-2 [When available]

Biological therapy is a type of treatment that works with your immune system. It can help fight cancer or help control side effects (how your body reacts to the drugs you are taking) from other cancer treatments like chemotherapy.

What is the difference between biological therapy and chemotherapy?

Biological therapy and chemotherapy are both treatments that fight cancer. While they may seem alike, they work in different ways. Biological therapy helps your immune system fight cancer. Chemotherapy attacks the cancer cells directly.

How does biological therapy fight cancer?

Doctors are not sure how biological therapy helps your immune system fight cancer. But they think it may:
  • Stop or slow the growth of cancer cells.
  • Make it easier for your immune system to destroy, or get rid of, cancer cells.
  • Keep cancer from spreading to other parts of your body.
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