Carcinoma

This page contains recent news articles, when available, and an overview of Carcinoma but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

News: Carcinoma

Breast Cancer Risk Is Not So Easy to Figure Out  -  23 Nov 2009
U.S. News & World ReportAmong them: women with a history of lobular carcinoma in situ—abnormal cells in the breast lobules, the milk-producing part of the breast. ...

The aggressiveness of urothelial carcinoma depends to a large extent on ...  -  23 Nov 2009
UroToday...vascular endothelial growth factor (VEGF)-C and VEGF-receptor 3 antibodies was performed in 83 patients with urothelial carcinoma who underwent radical ...

What makes skin cancer grow  -  23 Nov 2009
Times of IndiaIt is known that people with that particular strain are more at risk of getting a skin cancer called basal cell carcinoma – but were not sure why. ...

Patients with Metastatic Renal Cell Cancer Are Diagnosed Earlier and Have More ...  -  23 Nov 2009
Cancer Consultants...[1] The current study looked at risk factors in 789 patients with metastatic renal cell carcinoma treated between 1975 and 2007. ...

Opiate Painkillers May Encourage Spread Of Cancer  -  23 Nov 2009
Medical News TodayIn one study, they used bronchioloalveolar carcinoma cells and showed that MNTX blocked cancer-promoting signals and stopped tumor cell proliferation and ...

Chest CT Angiograms to Diagnose Pulmonary Embolism Twice as Likely to Find ...  -  23 Nov 2009
Medscape..."Small pulmonary nodules on chest CT scans could indicate bronchogenic carcinoma; however, these lesions are much more likely to be benign," William B. Hall ...

CytRx: Technical Breakout Imminent  -  23 Nov 2009
Seeking Alpha (blog)...and certain solid tumors in the US, and multiple myeloma, myelodysplastic syndromes and solid tumors other than hepatocellular carcinoma in Europe. ...

Endoscopic Ultrasound-Fine Needle Aspiration Predicts 5-year Survival in ...  -  23 Nov 2009
DG NewsAll 10 patients classified as having an endocrine carcinoma by EUS-FNA had the diagnosis confirmed by surgery. The five-year survival rates were 100% for ...

Spectrum and Handok Sign South Korean Development and Commercialization Deal ...  -  23 Nov 2009
Genetic Engineering News (press release)...and satraplatin is an orally administered platinum-derived chemotherapy agent in development for the treatment of non-small-cell lung carcinoma. ...

Range of Cancer-Fighting Agents Get FDA Nod  -  23 Nov 2009
Oncology Nursing NewsThis oral medication interferes with angiogenesis in the tumors of advanced renal cell carcinoma. In studies, progression-free survival averaged 9.2 months ...

'FlashForward': Renal cell carcinoma and Bob Dylan  -  ‎Nov 19, 2009‎
Zap2it.comWhat we didn't know before tonight, though, was that four weeks before the blackout Bryce learned that his stage four renal cell carcinoma had metastasized. ...

European CHMP Formally Adopts Negative Opinion on Oncophage®  -  ‎Nov 20, 2009‎
WELT ONLINEStudies with Oncophage have demonstrated efficacy signals in multiple cancers, including melanoma, glioma, colorectal, pancreatic, renal cell carcinoma, ...

Stopping breast cancer and fear at 'stage zero'  -  ‎Nov 20, 2009‎
Gloucester Daily TimesOncologists are also going to see a sharp drop in their ductal carcinoma in situ (DCIS) business. These small, non cancerous, calcified portions of a milk ...

NICE Appraisal Of Sorafenib For Advanced Hepatocellular Carcinoma  -  ‎Nov 20, 2009‎
Medical News Today (press release)The National Institute for Health and Clinical Excellence (NICE) is currently appraising the use of sorafenib for advanced hepatocellular carcinoma (HCC) in ...

Metastatic Squamous Cell Carcinoma Presenting as Diffuse and Punctate Cervical ...  -  ‎Nov 20, 2009‎
Journal of Ultrasound in Medicine (subscription)...lymph nodes and the utility of sonographically guided fine-needle aspiration biopsy (FNAB) in the setting of metastatic squamous cell carcinoma (SCC). ...

Neoadjuvant VEGF-Targeted Therapy in Renal Cell Carcinoma  -  ‎Nov 19, 2009‎
Renal and Urology NewsRecent therapeutic advances in metastatic renal cell carcinoma (RCC) have included agents targeted against vascular endothelial growth factor (VEGF). ...

Laryngeal tuberculosis presenting as a supraglottic carcinoma: a case report ...  -  ‎Nov 20, 2009‎
7thSpace Interactive (press release)Nowadays, it more closely resembles a laryngeal carcinoma than any other laryngeal illness.Case presentationWe describe the case of a 50-year-old Caucasian ...

Rhino responds well to cancer treatment  -  ‎Nov 16, 2009‎
abc7.com..."That was not healing, because there was squamous cell carcinoma inside. In a squamous cell carcinoma, radiation is the appropriate tool," said Greer. ...

New Medication Approved for Treated Advanced Renal Cell Carcinoma  -  ‎Nov 19, 2009‎
Renal and Urology NewsThe FDA has approved Votrient (pazopanib) for the treatment of advanced renal cell carcinomia (RCC). A once-daily, oral medication, pazopanib is an ...

Prospective study of daily low-dose nedaplatin and continuous 5-fluorouracil ...  -  ‎Nov 22, 2009‎
7thSpace Interactive (press release)Methods: Between January 2003 and June 2008, 33 patients with clinical stage I to IVB esophageal squamous cell carcinoma were enrolled. ...

ImmunoGen, Inc. Announces Encouraging Clinical Data with Its IMGN901 Compound ...  -  ‎Nov 17, 2009‎
WELT ONLINE..."To date, IMGN901 has demonstrated highly encouraging activity in the treatment of Merkel cell carcinoma and has been generally well tolerated,? commented ...

Transperitoneal laparoscopic right radical nephrectomy for renal cell ...  -  ‎Nov 18, 2009‎
7thSpace Interactive (press release)Nephron-sparing surgery (partial nephrectomy) results are similar to those of radical nephrectomy for small (<4 cm) renal tumors. However, in patients with ...

Proteo Inc./Proteo Biotech AG: European Medicines Agency EMEA Recommends ...  -  ‎Nov 16, 2009‎
WELT ONLINEPatients undergoing esophagectomy for esophagus carcinoma are currently being treated with Elafin within the framework of a Phase II clinical trial. ...

CD 9 and vimentin distinguish clear cell from chromophobe renal cell carcinoma  -  ‎Nov 18, 2009‎
7thSpace Interactive (press release)Clear cell renal cell carcinoma (ccRCC) and chromophobe renal cell carcinoma (chRCC) can usually be distinguished by histologic characteristics. ...

Declining recurrence among ductal carcinoma in situ patients treated with ...  -  ‎Nov 18, 2009‎
7thSpace Interactive (press release)IntroductionRandomized trials indicate that adjuvant radiotherapy plus tamoxifen decrease the 5-year risk of recurrence among ductal carcinoma in situ ...

Could my new 'freckle' be another basal cell carcinoma?  -  ‎Oct 28, 2009‎
CNNI have basal cell carcinoma. I have had two surgeries on my face. I have had a few frozen off as well. Was to go back to the doctor to get a checkup on the ...

CD10 expression in urothelial carcinoma of the bladder  -  ‎Nov 16, 2009‎
7thSpace Interactive (press release)The aim of this study was to evaluate CD10 expression in urothelial carcinoma of the urinary bladder and to determine the correlation between ...

XPD Codon 312 and 751 Polymorphisms, and AFB1 Exposure, and Hepatocellular ...  -  ‎Nov 17, 2009‎
7thSpace Interactive (press release)...variation in DNA repair capacity, which may be associated with risk of hepatocellular carcinoma (HCC) related to the exposure of aflatoxin B1 (AFB1). ...

NCCN updates renal cell carcinoma guidelines  -  ‎Nov 4, 2009‎
HemOncTodayThe drug was approved by the FDA to treat advanced renal cell carcinoma in October. The approval was based on data from a phase-3, open-label, ...

Early PET-CT predicts treatment response of head and neck cancer  -  ‎Nov 17, 2009‎
Curetoday.com (press release)NEW YORK (Reuters Health) - In patients with advanced squamous cell carcinoma of the head and neck, negative findings on post-treatment positron emission ...

Incidence of brain metastases in renal cell carcinoma treated with sorafenib ...  -  ‎Nov 12, 2009‎
UroTodayThis retrospective study evaluated the incidence of brain metastases in a subgroup of patients with metastatic renal cell carcinoma (RCC) who were randomly ...

UW-Platteville's resident physician gives talk about breast cancer  -  ‎Nov 4, 2009‎
Exponent OnlineThere are a few different types of breast cancer: Ductal carcinoma, lobular carcinoma, and invasive carcinoma. Invasive ductal carcinoma makes up about 90 ...

Vaccine Against HPV-16 Effective for Vulvar Intraepithelial Neoplasia  -  ‎Nov 6, 2009‎
Cancer Consultants...[1] Vascular intraepithelial neoplasia is a premalignant condition caused by HPV; VIN can lead to vulvar carcinoma. Patients may or may not be symptomatic, ...

ArQule Presents Data at AACR-NCI-EORTC Conference  -  ‎Nov 17, 2009‎
Trading Markets (press release)Growth of gastric carcinoma tumor xenografts in athymic mice was significantly inhibited after daily administration of a prototype compound for nine days, ...

Seattle Genetics Initiates Phase I Clinical Trial of Antibody-Drug Conjugate ...  -  ‎Nov 16, 2009‎
WELT ONLINESeattle Genetics, Inc. (Nasdaq: SGEN) today announced that it has initiated a phase I clinical trial of SGN-75 for metastatic renal cell carcinoma and ...

Investigation into the controversial association of Streptococcus gallolyticus ...  -  ‎Nov 19, 2009‎
7thSpace Interactive (press release)NF-kappaB and IL-8 mRNA expression was evaluated in tumorous and non-tumorous tissue sections of carcinoma and adenoma patients in comparison with that of ...

T cell-based immunotherapy of metastatic renal cell carcinoma: Modest success ...  -  ‎Nov 11, 2009‎
UroTodayMetastatic renal cell carcinoma (MRCC) remains a challenging malignancy to treat. Cancer immunotherapies have been extensively explored in melanoma and RCC ...

Incidental diagnosis of transitional cell carcinoma during percutaneous ...  -  ‎Nov 10, 2009‎
UroTodayThe aim of this study was to investigate the characteristics of patients who were incidentally diagnosed with transitional cell carcinoma (TCC) during ...

Failed cancer treatment doubly painful for widow  -  ‎Nov 16, 2009‎
Chicago TribuneThe 49-year-old Waukegan man, diagnosed with gastric carcinoma, had been given only months to live. His wife, Fanny Gonzalez, said employees at the Zion ...

Presence of Necrosis in Core Biopsy Predicts Close Margin in Ductal Carcinoma ...  -  ‎Nov 9, 2009‎
DG NewsCHICAGO -- November 9, 2009 -- Most data gathered by needle biopsy of in situ ductal carcinoma patients are of limited value in predicting ...

Metabolic profiling reveals key metabolic features of renal cell carcinoma ...  -  ‎Nov 11, 2009‎
UroTodayRecent evidence suggests that metabolic changes play a pivotal role in the biology of cancer and in particular renal cell carcinoma (RCC). ...

Left-sided inferior vena cava with renal carcinoma: A case report - Abstract  -  ‎Nov 11, 2009‎
UroTodayThe authors present a rare case of left-sided inferior vena cava (IVC) in a patient with renal cell carcinoma of the right kidney. ...

TARGET: biomarkers predicted OS in RCC  -  ‎Nov 17, 2009‎
HemOncTodaySeveral plasma biomarkers have been identified that may be predictive of OS in advanced renal cell carcinoma, according to the results of the TARGET study. ...

Basal cell carcinoma of the prostate: A case report and review of the ...  -  ‎Nov 10, 2009‎
UroTodayWe report a case of an adenoid cystic variant of basal cell carcinoma (BCC) of the prostate in a patient diagnosed following transurethral resection (TURP). ...

Comparing chemoradiotherapy with other modalities for treating unresectable ...  -  ‎Nov 10, 2009‎
American Journal of Hemotology and OncologyIn 2009, an estimated 42 470 new cases of pancreatic carcinoma will be diagnosed in the United States. Unfortunately, only 15% to 20% of these cases will be ...

Hepatocellular carcinoma  -  ‎Nov 13, 2009‎
European HospitalCases of hepatocellular carcinoma (HCC), one of the most frequently occurring cancers throughout the world, are expected to increase dramatically in the ...

Resistance to targeted therapy in renal-cell carcinoma - Abstract  -  ‎Nov 1, 2009‎
UroToday...mammalian target of rapamycin (mTOR), has produced robust clinical effects and revolutionised the treatment of metastatic renal-cell carcinoma (RCC). ...

Transgene: First Patient enrolled in Phase I Trial of TG4023 for  -  ‎Nov 21, 2009‎
Ethio Planet News...“The pre-clinical data for TG4023 has been very promising and there is a clear market need for an alternative treatment of hepatocellular carcinoma and ...

Local political veteran warns of the breast cancer that mammograms don't detect  -  ‎Nov 11, 2009‎
Tampabay.comBut each year, 20000 women develop invasive lobular carcinoma, a type of the disease which, in its early stages, doesn't show up on a mammogram and doesn't ...

Urachal tumour: case report of a poorly understood carcinoma  -  ‎Nov 7, 2009‎
7thSpace Interactive (press release)Urachal carcinoma is an uncommon neoplasm associated with poor prognosis.Case presentationA 45-year-old man was admitted with complaints of abdominal pain ...



Background information on Carcinoma [When available]

In medicine, carcinoma is any cancer that arises from epithelial cells. It is malignant by definition: carcinomas invade surrounding tissues and organs, and may spread to lymph nodes and distal sites (metastasis). Carcinoma in situ (CIS) is a pre-malignant condition, in which cytological signs of malignancy are present, but there is no histological evidence of invasion through the epithelial basement membrane.

Types of carcinoma

Carcinoma, like all neoplasia, is classified by its histopathological appearance. Adenocarcinoma and squamous cell carcinoma, two common descriptive terms for tumours, reflect the fact that these cells may have glandular or squamous cell appearances respectively. Severely anaplastic tumours might be so undifferentiated that they do not have a distinct histological appearance. Sometimes a tumour is referred to by the presumptive organ of the primary (eg carcinoma of the prostate) or the putative cell of origin (hepatocellular carcinoma, renal cell carcinoma).

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